These Very Low Compression (VLC) socks feature a ventilation channel to keep your feet cool all day long, are hand-linked to provide seamless toes and minimize exposure to blisters and have a very low binding top which have extra cross-stretch in the top (recommended for diabetics). The MedDry Moisture management fiber gives lasting comfort while the extra wide comfort top accommodates bodies' natural changes without binding. 83% MedDry™ polyester, 15% polyamide, 2% elastane. Accepted by the American Podiatric Medical Association (APMA). Small=Women 6-8, Medium=Women 8.5-10.5 or Men 7-9, Large=Women 11-13 or Men 9.5-11.5, X-Large=Men 12-14.